San Francisco 49ers QB Brock Purdy completed 15 of his 27 passes for 140 yards and an interception and rushed five times for 37 yards and lost a fumble in a 41-6 loss to the Seattle Seahawks in the Divisional Round. RB Christian McCaffrey (stinger) dealt with a stinger but managed 11 carries for 35 yards and caught five passes for 39 yards, and RB Jordan James added six carries for 28 yards and caught a seven-yard pass. TE Jake Tonges (foot) caught five passes for a team-high 59 yards before exiting with a foot injury, and WR Jauan Jennings had two grabs for 23 yards. WR Ricky Pearsall and WR Kendrick Bourne were both targeted twice, but neither caught a pass, and WR Demarcus Robinson gained a yard on his only catch. LB Dee Winters tied for the team lead with nine tackles, including three tackles for loss, and LB Eric Kendricks also had nine stops. S Malik Mustapha chipped in eight tackles and a sack.

San Francisco 49ers OG Spencer Burford (knee) and WR Jordan Watkins (calf) did not participate in practice Friday, Sept. 19, and have been ruled out for Week 3. WR Jauan Jennings (ankle, shoulder) did not practice and is listed as questionable. OG Connor Colby (groin) and QB Brock Purdy (shoulder, toe) were limited during practice and are listed as questionable. DE Yetur Gross-Matos (knee) did not practice but is not on the injury report. DE Nick Bosa (non-injury), RB Jordan James (finger), FB Kyle Juszczyk (concussion), RB Christian McCaffrey (calf), S Siran Neal (concussion) and OT Trent Williams (knee) fully participated in practice and are not on the injury report.

San Francisco 49ers OG Spencer Burford (knee) and WR Jordan Watkins (calf) did not participate in practice Friday, Sept. 19, and have been ruled out for Week 3. WR Jauan Jennings (ankle, shoulder) did not practice and is listed as questionable. OG Connor Colby (groin) and QB Brock Purdy (shoulder, toe) were limited during practice and are listed as questionable. DE Yetur Gross-Matos (knee) did not practice but is not on the injury report. DE Nick Bosa (non-injury), RB Jordan James (finger), FB Kyle Juszczyk (concussion), RB Christian McCaffrey (calf), S Siran Neal (concussion) and OT Trent Williams (knee) fully participated in practice and are not on the injury report.

San Francisco 49ers OG Spencer Burford (knee) and WR Jordan Watkins (calf) did not participate in practice Friday, Sept. 19, and have been ruled out for Week 3. WR Jauan Jennings (ankle, shoulder) did not practice and is listed as questionable. OG Connor Colby (groin) and QB Brock Purdy (shoulder, toe) were limited during practice and are listed as questionable. DE Yetur Gross-Matos (knee) did not practice but is not on the injury report. DE Nick Bosa (non-injury), RB Jordan James (finger), FB Kyle Juszczyk (concussion), RB Christian McCaffrey (calf), S Siran Neal (concussion) and OT Trent Williams (knee) fully participated in practice and are not on the injury report.

San Francisco 49ers OT Spencer Burford (knee) and WR Jauan Jennings (ankle, shoulder) did not participate in practice Thursday, Sept. 18. DE Yetur Gross-Matos (knee), FB Kyle Juszczyk (concussion) S Siran Neal (concussion), QB Brock Purdy (shoulder, toe), WR Jordan Watkins (calf) and OT Trent Williams (knee) were limited during practice. DE Nick Bosa (non-injury) RB Jordan James (finger) and RB Christian McCaffrey (calf) fully participated in practice.

San Francisco 49ers OT Spencer Burford (knee) and WR Jauan Jennings (ankle, shoulder) did not participate in practice Thursday, Sept. 18. DE Yetur Gross-Matos (knee), FB Kyle Juszczyk (concussion) S Siran Neal (concussion), QB Brock Purdy (shoulder, toe), WR Jordan Watkins (calf) and OT Trent Williams (knee) were limited during practice. DE Nick Bosa (non-injury) RB Jordan James (finger) and RB Christian McCaffrey (calf) fully participated in practice.

San Francisco 49ers DE Nick Bosa (non-injury), OT Spencer Burford (knee), DE Yetur Gross-Matos (knee), WR Jauan Jennings (ankle, shoulder), FB Kyle Juszczyk (concussion), RB Christian McCaffrey (calf), S Siran Neal (concussion) and OT Trent Williams (knee) did not participate in practice Wednesday, Sept. 17. QB Brock Purdy (shoulder, toe) was limited during practice, while RB Jordan James (finger) fully participated in practice.

San Francisco 49ers DE Nick Bosa (non-injury), OT Spencer Burford (knee), DE Yetur Gross-Matos (knee), WR Jauan Jennings (ankle, shoulder), FB Kyle Juszczyk (concussion), RB Christian McCaffrey (calf), S Siran Neal (concussion) and OT Trent Williams (knee) did not participate in practice Wednesday, Sept. 17. QB Brock Purdy (shoulder, toe) was limited during practice, while RB Jordan James (finger) fully participated in practice.

San Francisco 49ers QB Brock Purdy (shoulder, toe) did not participate in practice Friday, Sept. 12, and has been ruled out for Week 2. WR Jauan Jennings (shoulder) and OT Trent Williams (knee) were limited during practice and are listed as questionable. OG Ben Bartch (elbow, knee), DE Nick Bosa (non-injury), LB Luke Gifford (knee), RB Jordan James (finger), QB Mac Jones (knee), RB Christian McCaffrey (calf), OG Dominick Puni (knee) and WR Jordan Watkins (ankle) fully participated in practice and are not on the injury report.

San Francisco 49ers QB Brock Purdy (shoulder, toe) did not participate in practice Friday, Sept. 12, and has been ruled out for Week 2. WR Jauan Jennings (shoulder) and OT Trent Williams (knee) were limited during practice and are listed as questionable. OG Ben Bartch (elbow, knee), DE Nick Bosa (non-injury), LB Luke Gifford (knee), RB Jordan James (finger), QB Mac Jones (knee), RB Christian McCaffrey (calf), OG Dominick Puni (knee) and WR Jordan Watkins (ankle) fully participated in practice and are not on the injury report.