San Francisco 49ers RB Christian McCaffrey was named the 2025 NFL Comeback Player of the Year Award. He led the 49ers in both rushing and receiving yardage in 2025, totaling over 2,000 scrimmage yards after playing just four games in 2024.

San Francisco 49ers RB Christian McCaffrey eclipsed 2,000 yards from scrimmage for the third time in his career in 2025, and in the seasons after his previous two 2,000-yard campaigns, he played in a combined seven games. "You've got to be ready to play in the games as much as possible," McCaffrey said. "I'll do whatever it takes for this team."

San Francisco 49ers QB Brock Purdy completed 15 of his 27 passes for 140 yards and an interception and rushed five times for 37 yards and lost a fumble in a 41-6 loss to the Seattle Seahawks in the Divisional Round. RB Christian McCaffrey (stinger) dealt with a stinger but managed 11 carries for 35 yards and caught five passes for 39 yards, and RB Jordan James added six carries for 28 yards and caught a seven-yard pass. TE Jake Tonges (foot) caught five passes for a team-high 59 yards before exiting with a foot injury, and WR Jauan Jennings had two grabs for 23 yards. WR Ricky Pearsall and WR Kendrick Bourne were both targeted twice, but neither caught a pass, and WR Demarcus Robinson gained a yard on his only catch. LB Dee Winters tied for the team lead with nine tackles, including three tackles for loss, and LB Eric Kendricks also had nine stops. S Malik Mustapha chipped in eight tackles and a sack.

Updating a previous report, San Francisco 49ers RB Christian McCaffrey (stinger) returned to the Divisional Round game against the Seattle Seahawks after exiting with a stinger.

San Francisco 49ers RB Christian McCaffrey (undisclosed) did not start the second half of the Divisional Round game against the Seattle Seahawks after being checked out by trainers at the end of the second quarter.

San Francisco 49ers RB Christian McCaffrey faces the Seattle Seahawks in the Divisional Round, and McCaffrey gained 92 rushing yards on 30 carries in two meetings with Seattle in the regular season.

San Francisco 49ers QB Brock Purdy completed 18-of-31 passes for 262 yards, two touchdowns and two interceptions, while running nine times for 24 yards, in the NFC Wild Card game road win against the Philadelphia Eagles. RB Christian McCaffrey rushed 15 times for 48 yards, while posting six receptions for 66 yards and two touchdowns, including a 29-yard TD from WR Jauan Jennings. The latter had one reception for 45 yards on three targets and the scoring strike. WR Demarcus Robinson led the way with six receptions for 111 yards and a touchdown on seven targets, while FB Kyle Juszczyk absorbed all four targets for 49 yards, with TE Jake Tonges posted a 14-yard catch on three targets, stepping in for TE George Kittle (Achilles), who had one grab for six yards before leaving with a ruptured Achilles. LB Garret Wallow had 11 total stops with five solo tackles and a pass defensed, while LB Eric Kendricks, a former Eagle, had 10 total stops with seven solo tackles, two stops for loss and a pass break-up to seal the win.

San Francisco 49ers LB Luke Gifford (quadriceps), WR Ricky Pearsall (ankle, knee) and LB Dee Winters (ankle) did not participate in practice Friday, Jan. 9, and are listed as questionable for the Wild Card playoff game. CE Renardo Green (ankle), DE Keion White (groin, hamstring) and OT Trent Williams (hamstring) were limited during practice and are listed as questionable. WR Jacob Cowing (hamstring) fully participated in practice but is listed as questionable. DE Yetur Gross-Matos (knee) did not practice but is not on the injury report. S Ji'Ayir Brown (rib), DT Kalia Davis (knee), DT Jordan Elliott (knee), TE George Kittle (ankle) and RB Christian McCaffrey (non-injury) fully participated in practice and are not on the injury report.

San Francisco 49ers RB Christian McCaffrey (non-injury) fully participated in practice Friday, Jan. 9, and is not on the injury report for the Wild Card playoff game.

San Francisco 49ers LB Luke Gifford (quadriceps), WR Ricky Pearsall (ankle, knee), DE Keion White (groin, hamstring) and LB Dee Winters (ankle) did not participate in practice Thursday, Jan. 8. DT Jordan Elliott (knee), DE Yetur Gross-Matos (knee), TE George Kittle (ankle) and OT Trent Williams (hamstring) were limited during practice. S Ji'Ayir Brown (rib), WR Jacob Cowing (hamstring), DT Kalia Davis (knee) and RB Christian McCaffrey (non-injury) fully participated in practice.