San Francisco 49ers S Talanoa Hufanga (wrist) may not return to the active roster again this season, according to head coach Kyle Shanahan. The team is hoping Hufanga will be able to play again this season.

San Francisco 49ers S Talanoa Hufanga (wrist) was placed on the Reserve/Injured list Wednesday, Oct. 9.

San Francisco 49ers DT Jordan Elliott (knee), LB Demetrius Flannigan-Fowles (calf), S Talanoa Hufanga (wrist) and PK Jake Moody (ankle) did not participate in practice Wednesday, Oct. 9, and have been ruled out for Week 6. WR Chris Conley (oblique) and CB Charvarius Ward (knee) were limited during practice and are listed as questionable. S Ji'Ayir Brown (ankle), LB Fred Warner (ankle) and WR Jacob Cowing (shoulder) fully participated in practice and are not on the injury report.

San Francisco 49ers Talanoa Hufanga (wrist), LB Demetrius Flannigan-Fowles (calf), PK Jake Moody (ankle) and DT Jordan Elliott (knee) did not practice on Tuesday, Oct. 8. CB Charvarius Ward (knee), WR Chris Conley (oblique), TE George Kittle (ribs), LB Fred Warner (ankle) and S Ji'Ayir Brown (ankle) were limited. WR Jacob Cowing (shoulder) practiced in full. The 49ers held a walk-through on Tuesday, so the report is an estimation.

San Francisco 49ers S Talanoa Hufanga (wrist) recently suffered ligament damage in his wrist and is expected to miss at least one month, according to head coach Kyle Shanahan on Tuesday, Oct. 8.

San Francisco 49ers WR Chris Conley (oblique), DT Jordan Elliott (knee), LB Demetrius Flannigan-Fowles (calf), S Talanoa Hufanga (wrist), PK Jake Moody (ankle) and CB Charvarius Ward (knee) did not participate in practice Monday, Oct. 7. S Ji'Ayir Brown (ankle) and LB Fred Warner (ankle) were limited during practice, while WR Jacob Cowing (shoulder) fully participated in practice. The 49ers did not hold a practice Monday, so the practice report is an estimation.

San Francisco 49ers S Talanoa Hufanga (wrist) left the Week 5 game against the Arizona Cardinals due to a wrist injury, and he is considered questionable to return.

San Francisco 49ers LB Demetrius Flannigan-Fowles (calf) and DE Yetur Gross-Matos (knee) did not participate in practice Friday, Oct. 4, and have been ruled out for Week 5. WR Chris Conley (oblique) did not practice and is listed as doubtful. CB Isaac Yiadom (thigh) did not practice and is listed as questionable. WR Jacob Cowing (shoulder) and LB Fred Warner (ankle) were limited during practice and are listed as questionable. DT Kalia Davis (knee) fully participated in practice but is listed as questionable. DT Jordan Elliott (knee), DT Kevin Givens (triceps), S Talanoa Hufanga (ankle), FB Kyle Juszczyk (shoulder), OT Trent Williams (non-injury) and LB Dee Winters (ankle) fully participated in practice and are not on the injury report.

San Francisco 49ers WR Chris Conley (oblique), WR Jacob Cowing (shoulder), DE Yetur Gross-Matos (knee), LB Fred Warner (ankle) and LB Demetrius Flannigan-Fowles (calf) did not participate in practice Thursday, Oct. 3. LB Dee Winters (ankle), DT Jordan Elliott (knee), DT Kevin Givens (triceps), S Talanoa Hufanga (ankle) and CB Isaac Yiadom (thigh) were limited during practice. OT Trent Williams (non-injury), DT Kalia Davis (knee) and FB Kyle Juszczyk (shoulder) fully participated in practice.

San Francisco 49ers WR Chris Conley (oblique), WR Jacob Cowing (shoulder), DE Yetur Gross-Matos (knee), LB Fred Warner (ankle) and LB Dee Winters (ankle) did not participate in practice Wednesday, Oct. 2. DT Jordan Elliott (knee), LB Demetrius Flannigan-Fowles (calf), DT Kevin Givens (triceps), S Talanoa Hufanga (ankle) and OT Trent Williams (non-injury) were limited during practice. DT Kalia Davis (knee) and FB Kyle Juszczyk (shoulder) fully participated in practice.